Data on the burden of disease, costs of illness, and cost-effectiveness of vaccines are needed to facilitate the
use of available anti-typhoid vaccines in developing countries. This one-year prospective surveillance was
carried out in an urban slum community in Delhi, India, to estimate the costs of illness for cases of typhoid
fever. Ninety-eight culture-positive typhoid, 31 culture-positive paratyphoid, and 94 culture-negative cases
with clinical typhoid syndrome were identified during the surveillance. Estimates of costs of illness were